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葛蓓孛

      

葛蓓孛,女,1984年6月出生,黑龙江哈尔滨人。现任中国农业科学院植物保护研究所生物防治研究室副主任、副研究员、硕士生导师。兼任中国植物保护学会生物防治专业委员会副秘书长。

2007年获齐齐哈尔大学园林学学士学位,2010年获东北林业大学园林植物与观赏园艺学硕士学位,2013年获中国农业大学果树学博士学位。2019年9月—2020年3月,美国加州大学伯克利分校,劳伦斯伯克利国家重点实验室访问学者。2013年—至今,中国农业科学院植物保护研究所从事科研工作。

长期从事生物杀菌剂产品创制及生物防治应用技术研究,重点以链霉菌次级代谢产物为研究对象,探索生物合成调控机理、优化发酵条件及产品加工工艺,建立生物农药配套使用技术规程,为蔬菜病害绿色防控提供产品和技术支持。发表论文30余篇,其中以第一作者/通讯作者在Frontiers in Microbiology,BMC Microbiology,Applied in Microbiology and Biotechnology,PLOS One,Biological Control等刊物发表SCI论文10余篇,授权国家发明专利11项。主持国家自然科学基金、国家重点研发计划子课题、国家外专局引智示范推广项目、中央级科研院所基本科研业务费项目、广西科技重大专项课题、国际杰出青年科学家来华工作计划等20余项;参加公益性行业(农业)专项、863、中韩“生物农药研究与应用”等科研项目的研究工作。

联系方式

电话:010-62815942

Email:bbge@ippcaas.cn; gbbcsx@126.com

 

主要代表性论文(#第1作者,*通讯作者)

1.WeiQiuhe#, Ayme Aung#, Liu Binghua, Ma Jinjin, Shi Liming, Zhang Kecheng, Ge Beibei*. Overexpression of wysR gene enhances wuyiencin biosynthesis in ΔwysR3 mutant strain from Streptomyces wuyiensis CK-15. Journal of Applied Microbiology, 2020, doi:10.1111/jam.14629

2.Shi Liming, Liu Binghua, Wei Qiuhe, Ge Beibei*, Zhang Kecheng*. Genome-wide transcriptomic analysis of the response of Botryis cinerea to wuyiencin. PLOS one, 2020,15(4): e0224643

3.Ei Mon Myo#, Ge Beibei#, Ma Jinjin,Cui Hailan, Shi Liming, Jiang Mingguo, Zhang Kecheng*. Indole-3-acetic acid production by Streptomyces fradiae NKZ-259 and its formulation to enhance plant growth. BMC Micriobiology. 2019, 19: 155

4.Ei Mon Myo, Liu Binghua, Ma Jinjin, Shi Liming, Jiang Mingguo, Zhang Kecheng, Ge Beibei*. Evaluation of Bacillus velezensis NKG-2 for bio-control activities against fungal disease and potential plant growth promotion. Biological Control, 2019, 134:23-31

5.Shi Liming, Ge Beibei, Liu Binghua, Liu Xingang, Jiang Mingguo, Zhang Kecheng*. Impact of Wuyiencin Application on the Soil Microbial Community and Fate of Typical Antibiotic Resistance Genes. Scientific Reports, 2019, doi.org/10.1038/s41598-019-40389-w

6.Shi Liming, Ge Beibei, Wang Jinzi, Liu Binghua, Ma Jinjin, Wei Qiuhe, Zhang Kecheng*. i-TRAQ-based protemic analysis reveals the mechanisms of Botrytis cinerea controlled with Wuyiencin. BMC Microbiology, 2019, 19:280

7.Liu Binghua#, Ge Beibei#, Ma jinjin, Wei Qiuhe, Abid Ali Khan, Shi Liming, Zhang Kecheng*. Identification of wysPII as an Activator of Morphological Development in Streptomyces albulus CK-15. Frontiers in Microbiology, 2018, 9:02550

8.Shi liming#, Thin Thin Nwet#, Ge Beibei, Zhao Wenjun, Liu Binghua, Cui hailan, Zhang Kecheng*.Antifungal and plant growth-promoting activities of Streptomyces roseoflavus strain NKZ-259. Biological control, 2018, 125: 57-64

9.Liu Binghua, Ge Beibei, Azhar Noreen, Zhao Wenjun, Cui hailan, Zhang kecheng. Complete genome sequence of Bacillus methylotrophicus strain NKG-1, isolated from the changbai moutains, China. Genome Announcements,2017, 6: e01454-17

10.Ge Beibei, Liu Binghua, ThinnThinnNwet, Zhao Wenjun, Shi Liming, Zhang Kecheng*. Bacillus methylotrophicus strain NKG-1, Isolated from Changbai Mountain, China, has Potential Applications as a Biofertilizer or Biocontrol Agent. PLOS one, 2016, 11(11) : e0166079

11.Ge Beibei#, Liu Yan#, Liu Binghua, Zhao Wenjun, Zhang Kecheng*. Characterization of novel DeoR-family member from Streptomyces ahygroscopicus strain CK-15 that acts as a repressor of morphological development. Applied microbiology and Biotechnology, 2016, 100: 8819-8828

12.Ge Beibei, Cheng Yan, Liu Yan, Liu Binghua, Zhang Kecheng*. Biological control of Botrytis cinerea on tomato plants using Streptomyces ahygroscopicus strain CK-15. Letter in applied microbiology, 2015, 61: 596-602

13.Ge Beibei, Liu Yan, Liu Binghua, Zhang Kecheng*. Draft genome sequence of Streptomyces ahygroscopicus subsp. wuiensis CK-15, isolated from soil in Fujian Province, China. Genome announcements, 2015, 3 (5): e01125-15

14.Liu Yanyan, RyuHojin, GeBeibei, Pan Guohui, Sun Lei, Park Kyungseok, Zhang Kecheng*. Improvement of wuyiencin biosynthesis in Streptomyces wuyiensis CK-15 by identification of a key regulator, WysR. Journal of Microbiology and Bio-technology, 2014, 24 (12): 1644-1653

15.王威, Thinzar Toe, 张亚, 张克诚, 姜明国, 张维, 施李鸣, 葛蓓孛*. 一株烟草肠杆菌 (Enterobacter tabaci) S4菌株的鉴定及其效果测定. 农业资源与环境学报, 2020, 37 (3): 407-412

16.葛蓓孛, 刘炳花, 赵文珺, 麻金金, 施李鸣, 张克诚. 武夷菌素高产菌株选育及应用研究进展. 中国生物防治学报, 2017, 33 (6): 767-773

17.葛蓓孛, 王家旺, 刘彦彦, 刘炳花, Park Kyungseok, Park Yongsoon, 张克诚.武夷菌素高产基因工程菌发酵培养基的优化. 中国生物防治学报, 2016, 32 (5): 1-8

18.葛蓓孛, 杨振娟, 檀贝贝, 刘彦彦, 刘艳, 孙蕾, 张克诚. 武夷菌素部分生物合成基因簇的克隆和分析, 中国生物防治学报, 2014, 30 (5): 678-684