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朱勋

      

 

朱勋,男,1985年11月出生,山东济宁人,博士,副研究员,主要研究方向:昆虫分子生物学。2016年中国农业科学院“青年英才计划D类人选”。
       2008年获黑龙江大学生物技术专业学士学位,2011年获黑龙江大学微生物学硕士学位,2014年获华中农业大学农药学博士学位。2014-2015年在中国农业科学院蔬菜花卉研究所开展博士后研究工作。曾担任第26届北京博士后联谊会理事会秘书长,第11届中国农业科学院博士后联谊会理事会理事长。2016年7月以中国农业科学院“青年英才计划D类人选”进入中国农业科学院植物保护研究所工作,聘为副研究员。
       朱勋主要从事农业昆虫分子生物学相关研究工作。系统研究了小菜蛾对Bt Cry1Ac杀虫晶体蛋白的抗性机理,利用高世代回交法首次建立抗Cry1Ac近等基因系小菜蛾种群,为Bt抗性机理的研究提供了理想的实验材料;利用这些特异的实验材料,系统开展抗性遗传方式、抗性适合度以及交互抗性谱研究,和多组学联合分析研究,为昆虫Bt抗性分子机理的完整揭示,提供必要的数据支持。完成首个农业害虫的蛋白质基因组研究工作,研究成果以第一作者发表在蛋白质顶尖期刊Molecular &Cellular Proteomics(IF > 6.0)上。先后主持国家自然科学青年基金、中国博士后特别资助基金、中国博士后面上基金,共发表国内外期刊论文27篇,获得国家发明专利10项,在Molecular & Cellar Proteomics、PLoS Genetics、Insect Biochemistry and Molecular Biology、Pest Management Science、、International Journal of Biological Sciences、PLoS ONE、Journal of Invertebrate Pathology、Gene、Journal of Economic Entomology等SCI源杂志上发表17篇文章。

近期作为通讯作者发表的代表性论文
1、Xun Zhu, Shangbo Xie, Jean Armengaud, Wen Xie, Zhaojiang Guo, Shi Kang,  Qingjun Wu, Shaoli Wang, Jixing Xia, Rongjun He, Youjun Zhang. Tissue-specific Proteogenomic Analysis of Plutella xylostella Larval Midgut Using a Multi-algorithm Pipeline. Molecular & Cellular Proteomics.(IF5-years=6.632) 2016,15: 1791-1807.
2、Xun Zhu, Yanyuan Lei, Yanjv Yang, Simon W. Baxter, Jianhong Li, Qingjun Wu, Shaoli Wang, Wen Xie, Zhaojiang Guo, Wei Fu, Youjun Zhang. Construction and Characterization of Near Isogenic Plutella xylostella (Lepidoptera: Plutellidae) Strains Resistant to Cry1Ac toxin. Pest Management Science (IF5-years=3.116) 2015,71(2), 225-233.
3、Xun Zhu,Miao Yuan, Muhammad Shakeel, Youjun Zhang, Shaoli Wang, Xin Wang, Sha Zhan, Tinghao Kang, Jianhong Li. Selection and Evaluation of Reference Genes for Expression Analysis Using qRT-PCR in the Beet Armyworm Spo-doptera exigua (Lepidoptera: Noctuidae) PLoS ONE, (IF5-years=4.015) 2014, 9(1): e84730. doi:10.1371/journal.pone.0084730. (IF=3.234)
4、Xun Zhu, Yanjv Yang,Qingjun Wu, Shaoli Wang, Wen Xie, Zhaojiang Guo, Jixing Xia, Shi Kang, Youjun Zhang.Lack of fitness costs and inheritance of resistance to Bacillus thuringiensis Cry1Ac toxin in a near-isogenic strain of Plutella xylostella (Lepidoptera:Plutellidae). Pest Management Science. (IF5-years=3.116)2016, 72:289–297.
5、Yanyuan Lei, Xun Zhu, Wen Xie, Qingjun Wu, ShaoliWang, Zhaojiang Guo, Baoyun Xu , Xianchun Li, Xuguo Zhou, Youjun Zhang. Midgut transcriptome response to a Cry toxin in the diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae). Gene, (IF: 2.246) 2014, 533(1):180-187.
6、Muhammad Shakeel, Xun Zhu, Ting-Hao Kang, Hu Wan, Jian-Hong Li. Selection of Reference Genes for Quantitative Gene Expression Studies in Cotton Bollworm, Helicoverpa armigera (Lepidoptera: Noctuidae) Journal of Asia-Pacific Entomology (IF:0.875) 2015 doi:10.1016/j.aspen.2015.01.001.
7、Zhaojiang Guo, Shi Kang, Xun Zhu, Qingjun Wu, Shaoli Wang, Wen Xie, Youjun Zhang.Down-regulation of a novel ABC transporter gene (Pxwhite) is associated with Cry1Ac resistance in the diamondback moth, Plutella xylostella (L.) Insect Biochemistry and Molecular Biology (IF: 4.052) 2015, 59:30-40.
8、Zhaojiang Guo, Shi Kang, Xun Zhu, Jixing Xia, Qingjun Wu, Shaoli Wang, Wen Xie, and Youjun Zhang. The novel ABC transporter ABCH1 is a potential target for RNAi-based insect pest control and resistance management. Scientific Reports (IF: 5.578) 2015, 5:13728. DOI: 10.1038/srep13728
9、Zhaojiang Guo, Shi Kang, Xun Zhu, Qingjun Wu, Shaoli Wang, Wen Xie, Youjun Zhang.The midgut cadherin-like gene is not associated with resistance to Bacillus thuringiensis toxin Cry1Ac in Plutella xylostella (L.). Journal of Invertebrate Pathology (IF:2.743)2015, 126: 21–30.
10、Caihua Shi, Fengshan Yang, Xun Zhu, Erxia Du , Yuting Yang , Shaoli Wang , Qingjun Wu Youjun Zhang. Evaluation of Housekeeping Genes for Quantitative Real-Time PCR Analysis ofBradysiaodoriphaga(Diptera: Sciaridae)[J]. International Journal of Molecular Sciences, 2016, 17(7):1034.
11、Miao Yuan, Yanhui Lu, Xun Zhu, Hu Wan, Muhammad Shakeel, Sha Zhan, Byung-Rae Jin, Jianhong Li. Selection and evaluation of potential reference genes for gene expression analysis in the brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae) using reverse- transcription quantitative PCR. PLoS ONE, (IF: 4.015) 2014, 9(1):e86503.doi:10.1371/journal.pone.0086503
12、Zhaojiang Guo, Shi Kang, Defeng Chen, Qingjun Wu, Shaoli Wang, Wen Xie, Xun Zhu, Simon W. Baxter, Juan Luis Jurat-Fuentes, Youjun Zhang. MAPK Signaling Pathway Alters Expression of Midgut ALP and ABCC Genes and Causes Resistance to Bacillus thuringiensis Cry1Ac Toxin in Diamondback Moth. PLoS Genetics (IF: 7.153)2015, 11, e1005124.
13、Jixing Xia, Zhaojiang Guo, Zezhong Yang, Xun Zhu, Shi Kang, Xin Yang, Fengshan Yang, Qingjun Wu, Shaoli Wang, Wen Xie, Weijun Xu, Youjun Zhang. Proteomics-based identification of midgut proteins correlated with Cry1Ac resistance in Plutella xylostella (L.) Pesticide Biochemistry and Physiology (IF: 2.079) doi: 10.1016/j.pestbp.2016.01.002.
14、Wen Xie, Yanyuan Lei, Wei Fu, Zhongxia Yang, Xun Zhu, Zhaojiang Guo, Qingjun Wu, Shaoli Wang, Baoyun Xu, Xuguo Zhou, Youjun Zhang. Tissue-Specific Transcriptome Profiling of Plutella xylostella Third Instar Larval Midgut, International Journal of Biological Science (IF: 4.223) 2012,8(8):1142-1155.
15、Wenxiang Li, Yuting Yang, Wen Xie, Qingjun Wu, Baoyun Xu, Shaoli Wang, Xun Zhu, Shijun Wang, Youjun Zhang. Effects of Temperature on the Age-Stage, Two-sex Life Table of Bradysia odoriphaga (Diptera: Sciaridae) Journal of Economic Entomology. (IF:1.804) 2015 DOI: 10.1093/jee/tou011.
16、Muhammad Shakeel, Muhammad Farooq, Wajid Nasim, Waseem Akram, Fawad Zafar Khan, Waqar Jaleel, Xun Zhu, Haichen Yin, Shuzhong Li, Shah Fahad, Saddam Hussain, Bhagirath Singh Chauhan, Fengliang Jin. Environment polluting conventional chemical control compared to an environmentally friendly IPM approach for control of diamondback moth, Plutella xylostella (L.), in China: a review. Environ Sci Pollut Res. 2017, DOI 10.1007/s11356-017-8996-3.
17、Jun Shen, Dong yang Li, Shuzhen Zhang, Xun Zhu, Hu Wan, Jian hong Li. Fitness and inheritance of metaflumizone resistance in Plutella xylostella.Pesticide Biochemistry and Physiology (IF: 2.079) 2017, 139: 53-59.